Diseases Treated by Blood Stem Cells

Many serious or life-threatening diseases have already been treated with cord blood. The following is a list of diseases that have been treated internationally with cord blood and other sources of the same type of stem cell, like bone marrow.

The newborn may be able to use his or her cord blood for some of the conditions on this list, but not all. In some cases, a matched sibling’s stem cells would be the first choice. Some of the conditions on this list, including the regenerative medicine uses, are experimental and are in clinical trials. Source: Medical literature and clinicaltrials.gov.

Leukemias, Lymphomas and Other Blood Cancers

Acute Biphenotypic Leukemia
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Acute Undifferentiated Leukemia
Adult T Cell Leukemia/Lymphoma
Chronic Lymphocytic Leukemia (CLL)
Chronic Myelogenous Leukemia (CML)
Hodgkin’s Lymphoma
Juvenile Chronic Myelogenous Leukemia (JCML)
Juvenile Myelomonocytic Leukemia (JMML)
Multiple Myeloma
Myeloid/Natural Killer (NK)
Cell Precursor Acute Leukemia
Non-Hodgkin’s Lymphoma
Prolymphocytic Leukemia
Plasma Cell Leukemia
Waldenstrom’s Macroglobulinemia

Other Cancers

Brain Tumors
Ewing Sarcoma
Neuroblastoma
Ovarian Cancer
Renal Cell Carcinoma
Rhabdomyosarcoma
Small-Cell Lung Cancer
Testicular Cancer
Thymoma (Thymic Carcinoma)

Bone Marrow Failure Disorders

Aplastic Anemia (Severe)
Blackfan-Diamond Anemia
Congenital Amegakaryocytic Thrombocytopenia (CAT)
Congenital Cytopenia
Congenital Dyserythropoietic Anemia
Dyskeratosis Congenita
Fanconi Anemia
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Pure Red Cell Aplasia

Hemoglobinopathies

Beta Thalassemia Major
Sickle Cell Disease

Histiocytic Disorders

Hemophagocytic Lymphohistiocytosis (HLH)
Hemophagocytosis
Langerhans?Cell Histiocytosis (Histiocytosis X)

Myelodysplastic/Myeloproliferative Disorders

Acute Myelofibrosis
Agnogenic Myeloid Metaplasia (Myelofibrosis)
Amyloidosis
Chronic Myelomonocytic Leukemia (CMML)
Essential Thrombocythemia
Polycythemia Vera
- Refractory Anemia with Excess Blasts (RAEB)
- Refractory Anemia with Excess Blasts in Transition (RAEB-T)
- Refractory Anemia with Ringed Sideroblasts (RARS)

Inherited Metabolic Disorders

Fucosidosis
Gaucher Disease
Hunter Syndrome (MPS-II)
Hurler Syndrome (MPS-IH)
Krabbe Disease
Lesch-Nyhan Syndrome
Mannosidosis
Maroteaux-Lamy Syndrome (MPS-VI)
Metachromatic Leukodystrophy
Mucolipidosis II (I-cell Disease)
Neuronal Ceroid Lipofuscinosis (Batten Disease)
Niemann-Pick Disease
Sandhoff Disease
Sanfilippo Syndrome (MPS-III)
Scheie Syndrome (MPS-IS)
Sly Syndrome (MPS-VII)
Tay Sachs

Inherited Immune System Disorders

Chronic Granulomatous Disease
Congenital Neutropenia
Leukocyte Adhesion Deficiency
Severe Combined Immunodeficiencies (SCID) including:
- Adenosine Deaminase Deficiency
- Bare Lymphocyte Syndrome
- Chediak-Higashi Syndrome
- Kostmann Syndrome
- Omenn Syndrome
- Purine Nucleoside Phosphorylase Deficiency
- Reticular Dysgenesis
Wiskott-Aldrich Syndrome
X-Linked Lymphoproliferative Disorder